Total synthesis of ulongamide A, a cyclic depsipeptide isolated from marine cyanobacteria Lyngbya sp. |
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| Authors: | Cuauhtémoc Alvarado Ángel Guzmán |
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| Institution: | Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, Coyoacan, 04510 México, DF, Mexico |
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| Abstract: | A total synthesis of ulongamide A (1), a cytotoxic natural cyclic depsipeptide, was achieved by a convergent route involving coupling of the fragments 7 and 8 to the pentapeptide 24, and subsequent cyclization thereof after prior removal of the t-Boc protecting groups. |
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| Keywords: | Ulongamide A Cyanobacteria Cyclodepsipeptides |
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