Chemoenzymatic dynamic kinetic resolution of secondary amines |
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Authors: | Matthew Stirling John Blacker |
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Affiliation: | a Department of Chemical and Biological, Sciences, The University of Huddersfield, Huddersfield HD1 3DH, UK b NPILPharma, Leeds Road, Huddersfield HD1 9GA, UK |
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Abstract: | The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee. |
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