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Chemoenzymatic dynamic kinetic resolution of secondary amines
Authors:Matthew Stirling  John Blacker
Affiliation:a Department of Chemical and Biological, Sciences, The University of Huddersfield, Huddersfield HD1 3DH, UK
b NPILPharma, Leeds Road, Huddersfield HD1 9GA, UK
Abstract:The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.
Keywords:
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