Feroniellides A and B, apotirucallane triterpenes with novel cyclic acetals from Feroniella lucida |
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| Authors: | Preecha Phuwapraisirisan Serm Surapinit Santi Tip-pyang |
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| Institution: | a Natural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand
b Natural Products Research Section, Research Division, National Cancer Institute, Bangkok 10400, Thailand |
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| Abstract: | The isolation and structure elucidation of two new triterpenes named feroniellides A (1) and B (2) from Feroniella lucida are described. Feroniellide A has a novel dioxabicyclic 3.2.1]octane moiety, and feroniellide B is the C-3 epimer of the known triterpenoid 3. Their overall structures and relative configurations were established by combined spectral data analysis. The cytotoxicity of 1 and 2 was also evaluated against human KB and HeLa carcinoma cells. |
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| Keywords: | Feroniella lucida Rutaceae Triterpene Cytotoxic Feroniellide |
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