Aminocatalysis of the Baylis-Hillman reaction: an important solvent effect |
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Authors: | Huw J. Davies |
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Affiliation: | School of Chemistry, Main Building, Cardiff University, Park Place, Cardiff, CF10 3AT, UK |
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Abstract: | Examination of the aminocatalytic Baylis-Hillman reaction in the presence of proline and imidazole has revealed that water plays a crucial role in the acceleration of the reaction, allowing for excellent yields of the adduct between methyl vinyl ketone and a variety of aldehydes. |
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