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Highly practical boronic acid surrogates for the Suzuki-Miyaura cross-coupling
Authors:Hélène BoninRodrigue Leuma-Yona  Bruno MarchioriPatrice Demonchaux  Emmanuel Gras
Institution:a CNRS, Université Paul Sabatier, LSPCMIB, 118, route de Narbonne, F-31062 Toulouse Cedex 9, France
b Minakem, 145, Chemin des Lilas, F-59310 Beuvry-La-Forêt, France
c CNRS, LCC (Laboratoire de Chimie de Coordination), 205 route de Narbonne, F-31077 Toulouse, France
d Université de Toulouse, UPS, INPT, LCC, F-31077 Toulouse, France
Abstract:Boronic acids and esters are well known substrates for the Suzuki-Miyaura cross-coupling. Yet their isolation can sometimes be tedious. We report here that the use of aryl dioxazaborocanes afford a simple isolation procedure while keeping a high efficiency in the cross-coupling process.
Keywords:Palladium  Cross-coupling  Biaryls  Boron  Catalysis
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