One-pot synthesis of benzothiazolines and napthathiazolines via cascade ortho-lithiation, cyclisation and elimination of N-arylsulfonyl lactams |
| |
| Authors: | Harling John D Steel Patrick G Woods Tom M Yufit Dmitry S |
| |
| Affiliation: | GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts, UK SG1 2NY. |
| |
| Abstract: | ortho-Lithiation of cyclic aryl sulfonamides in the presence of phosphoryl chloride provides a very simple entry to fused polycyclic sultams (benzothiazolines and naphthathiazolines). |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
