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吲哚啉螺吡喃化合物光致变色性能的研究及在生物细胞成像中的应用
引用本文:谈婷婷,张瑜,刘水平,刘峻,陈彦模,陈龙.吲哚啉螺吡喃化合物光致变色性能的研究及在生物细胞成像中的应用[J].影像科学与光化学,2008,26(6):482-488.
作者姓名:谈婷婷  张瑜  刘水平  刘峻  陈彦模  陈龙
作者单位:东华大学, 材料科学与工程学院, 纤维改性国家重点实验室, 上海, 201620
基金项目:青年教师科研启动基金项目
摘    要:吲哚啉螺吡喃是一种重要的光致变色化合物,由于具有良好的变色回复性、抗疲劳性而得到广泛的关注.本文合成了1′-羟乙基-3′,3′-二甲基吲哚啉-6-硝基螺吡喃,研究了该化合物在紫外-可见光交替照射下紫外吸收强度的变化,并测试了光照前后化合物的荧光光谱.在开环态时,化合物具有优良的荧光性能,可以成功应用于细胞成像,在活细胞中可获得清晰的荧光成像图,同时也可以发挥螺吡喃光致变色可循环、耐疲劳等优势.

关 键 词:吲哚啉螺吡喃  紫外-可见光回复  荧光  细胞成像  
收稿时间:2008-04-28

Investigation of Photochromic Properties of Indolinospiropyran and Application in Bioimaging
TAN Ting-ting,ZHANG Yu,LIU Shui-ping,LIU Jun,CHEN Yan-mo,CHEN Long.Investigation of Photochromic Properties of Indolinospiropyran and Application in Bioimaging[J].Imaging Science and Photochemistry,2008,26(6):482-488.
Authors:TAN Ting-ting  ZHANG Yu  LIU Shui-ping  LIU Jun  CHEN Yan-mo  CHEN Long
Institution:State Key Lab For Modification of Chemical Fibers and Polymer Materials, College of Science and Technology, Dong Hua University, Shanghai 201620, P. R. China
Abstract:Indolinospiropyran is a kind of photoresponsive compound,and it has attracted significant attention for its photoisomerization between two forms,excellent properties of fatigue counterac- tion.In this article,1'-(2-hydroxyethyl)-3',3'-dimethyl-6-nitriospiro (2H-1-benzopyran-2,2'-in- doline) was synthesized,and its absorption change by irradiation UV-vis as well as fluorescence spectral change was investigated.In ring-open form,because of its excellent fluorescence image in living cells,this compound can apply in bioimaging.Also,its properties of restorable and fatigue counteraction can be also well displayed.
Keywords:indolinospiropyran  restore by UV-vis  fluorescence  bioimaging
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