Synthesis of spiroketals under neutral conditions via a type III ring-rearrangement metathesis strategy |
| |
| Authors: | Mandel Jérémie Dubois Nathalie Neuburger Markus Blanchard Nicolas |
| |
| Institution: | Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse, Laboratoire de Chimie Organique et Bioorganique EA4566, 3 rue A. Werner, 68093 Mulhouse Cedex, France. |
| |
| Abstract: | A conceptually novel approach to spiro- and dispiroketals of various ring-sizes under neutral conditions has been designed which complements the classical thermodynamically driven tactic. Key steps involved the formation of α-alkoxyfurans, their 4+2] or 4+3] cycloaddition reactions and the ring-rearrangement metathesis of the resulting oxabicycles. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
