Study of the stereochemistry of N-H and N-vinyl-4,5,7-trimethyi-4,5,6,7-tetrahydropyrrolo[3,2-c]pyridines and their nitro derivatives by the method of 1H and 13C NMR

The configurations and conformational features of N-H and N-vinyl-4,5,7-trimethyl-4,5,6,7-tetrahydropyrrolo3,2-c]pyridines and their nitro derivatives were established by the method of ¹H and ¹³C NMR spectroscopy. It was shown that the conformational uniformity of the piperideine ring in the compounds studied is strongly dependent on the character of the substituents in the pyrrole ring. A method for the determination of the orientation of the substituent at the -position to the nitrogen atom of the piperideine ring, according to the direct ¹J_CH SSCC, was proposed.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 75–81, January, 1993.