Non-covalent stabilization of a beta-hairpin peptide into liposomes |
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| Authors: | Löwik Dennis W P M Linhardt Jeffrey G Adams P J Hans M van Hest Jan C M |
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| Affiliation: | Department of Organic Chemistry University of Nijmegen, Toernooiveld 1-U177, 6525 ED Nijmegen, The Netherlands. lowik@sci.kun.nl |
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| Abstract: | An oligopeptide modified on both the N- and C-termini with hydrophobic moieties was prepared on a solid phase and anchored into a liposome, stabilizing the fold of the peptide into a beta-hairpin, which would otherwise be a random coil. |
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