Efficient and mild synthesis of functionalized 2,3-dihydrofuran derivatives via domino reaction in water |
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| Authors: | Jian-Wu Xie Ping LiTing Wang Fei-Ting Zhou |
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| Affiliation: | Key Laboratory of the Ministry of Education for Advanced Catalysis Materials Department of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China |
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| Abstract: | An efficient and mild method for the synthesis of functionalized tricyclic 2,3-dihydrofurans, bicyclic 2,3-dihydrofurans, and other tetrasubstituted 2,3-dihydrofurans by domino reaction of 1,3-dicarbonyl compounds and α-bromonitroalkenes with a large substrate scope and excellent diastereoselectivity (only trans isomers) in moderate to excellent yield (up to 96%) has been reported. |
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