Mathematical modelling of percutaneous absorption |
| |
| Authors: | Gary P. Moss Simon C. Wilkinson Yi Sun |
| |
| Affiliation: | 1. The School of Pharmacy, Keele University, Keele, Staffordshire, UK;2. Medical Toxicology Centre, Wolfson Building, Institute for Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, UK;3. School of Engineering & Information Science, University of Hertfordshire, Hatfield, UK |
| |
| Abstract: | This review examines recent progress made in the field of modelling and predicting percutaneous absorption. It describes initial qualitative modelling and how quantitative approaches were pioneered and then developed, particularly in the context of the analysis of specific subsets of data. It then focuses on recent developments, including non-linear modelling and discusses recommendations in model construction, development and validation, suggesting that some models do not fit proposed guidelines. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
