Copper modified platinum electrode for amperometric detection of spectinomycin sulfate by anion-exchange chromatography

A La³⁺–Cu/Pt modified electrode was fabricated by electrodepositing process in CuSO₄ solution by adding a small amount of lanthium compound, and it was employed for direct current (DC) amperometric detection of spectinomycin by anion-exchange chromatography. Without derivatization, this method can simultaneously determine the main component and impurities in spectinomycin pharmaceutical raw material. Ease of preparation, being applied in DC detection mode and good catalytic stability confirmed the interests of this modified electrode as amperometric sensor for the determination of spectinomycin.