Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore |
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| Authors: | Franceschini Lorenzo Mikhailova Ellina Bayley Hagan Maglia Giovanni |
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| Institution: | Department of Chemistry, University of Leuven, 3001, Heverlee, Leuven, Belgium. |
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| Abstract: | The four DNA bases are recognized in immobilized DNA strands at high alkaline pH by nanopore current recordings. Ionic currents through the biological nanopores are also employed to measure the apparent pK(a) values of single nucleobases within the immobilised DNA strands. |
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