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Exploiting the 1,2,3‐Triazole Moiety to Generate Carbazole Molecular Architectures through Click Approach
Authors:Mohamed A Ameen  Kamal M El‐Shaieb  Asmaa H Mohamed  Fathy F Abdel‐Latif
Institution:Chemistry Department, Faculty of Science, El Minia University, El Minia, Egypt
Abstract:Reaction of 3,6‐dichlorocarbazole with propargyl bromide in the presence of a basic medium gave an N‐propargylated carbazole. The latter compound was converted into molecular architectures containing 1,2,3‐triazole moiety through Cu(I)‐catalyzed 1,3‐cycloaddition reaction with different azides. Similarly, 2‐azidomethyl benzothiazole was cliched with N‐Boc‐protected N´‐propargyl glutamate to give the biomolecule 2‐triazolylmethyl product.
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