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Synthesis of New 1, 10‐Phenanthroline Analogs as Potent Antimicrobial Agents Using Montmorillonite K‐10 as Catalyst
Authors:Ramakanth Pagadala  Praveen Chidurala  Venkateshwarlu Jetti  Jyotsna S. Meshram  Suresh Maddila  Sreekanth B. Jonnalagadda
Affiliation:1. School of Chemistry & Physics, University of KwaZulu‐Natal, Durban, South Africa;2. Department of Chemistry, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
Abstract:A series of new 1, 10‐phenanthroline derivatives are synthesized by the four‐component domino reactions of 8‐hydroxy quinoline, aromatic aldehydes, methyl/ethyl acetoacetate and ammonium acetate in the presence of zeolite (montmorillonite K‐10) using both conventional and microwave methods. Most of the new compounds possessed moderate to significant anti‐bacterial and anti‐fungal activities.
Keywords:
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