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A New and Efficient One‐Pot Synthesis of 2‐Fluoroalkyl Substituted Indoles
Authors:Zengxue Wang  Qingwen Ma
Institution:Lunan Pharmaceutical Group Corporation, Linyi, Shandong, China
Abstract:A new simple and efficient one‐pot synthesis of 2‐fluoroalkyl substituted indoles from 2‐aminobenzyl alcohols with fluorine‐containing carboxylic acids in the presence of Ph3P, CCl4, and NEt3 is described. Various kinds of 2‐fluoroalkyl substituted indole derivatives can be conveniently prepared.
Keywords:
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