Synthesis and Biological Activity Studies of Some Novel Mannich Bases of Benzotriazolyl Triazoles

A series of substituted phenyl methyl piperazine triazolyl benzotriazoles 4a , 4b , 4c , 4d , 4e , 4f , 4g have been synthesized through the Mannich reaction of substituted phenyl triazolyl benzotriazoles 3a , 3b , 3c , 3d , 3e , 3f , 3g . The substituted phenyl triazolyl benzotriazoles were prepared from benzotriazolyl acetohydrazide, where the cyclization was facilitated through ammonium acetate and aryl aldehydes. The IR, ¹H NMR, mass spectral data and elemental analysis were performed to assign the structure. All the newly synthesized compounds were screened for their antimicrobial and antioxidant activity.