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One‐Pot Domino Synthesis of 3‐Amino‐1,2‐dihydroisoquinolines |
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| Authors: | W. Hamri O. O. Shyshkina T. M. Tarasiuk T. A. Volovnenko K. Mesbah S. Rhouati Y. M. Volovenko V. V. Medviediev O. V. Shishkin |
| Affiliation: | 1. Laboratoire de Produits Naturels d'origine végétales et Synthèse Organique, Departement de Chimie, Faculté des sciences exactes, Université Constantine 1, Constantine, Algeria;2. Department of Chemistry, Kyiv Taras Shevchenko University, Kyiv, Ukraine;3. Division of Functional Materials Chemistry, SSI “Institute for Single Crystals” of National Academy of Science of Ukraine, Kharkiv, Ukraine;4. Department of Chemistry, V. N. Karazin Kharkiv National University, Kharkiv, Ukraine |
| Abstract: | A one‐pot method for the synthesis of 3‐amino‐7‐nitro‐1,2‐dihydroisoquinoline‐4‐carbonitriles from 2‐chloro‐5‐nitrobenzylamines and malononitrile has been developed. |
| Keywords: | Domino reaction dihydroisoquinoline X‐ray |