Synthesis of Indolo[2,3‐a]pyrrolo[3,4‐c]carbazoles via the Oxidative Cyclization of Bisindolylmaleimides with Pd(TFA)2/Cu(OAc)2 |
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| Authors: | Xuan Pan Ke Wang Bao He Guan Zhan Zhu Liu |
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| Institution: | State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People's Republic of China |
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| Abstract: | A new synthetic approach for the synthesis of indolo2,3‐a]pyrrolo3,4‐c]carbazoles based on the Cu2+/Pd2+ catalytic system is described. The optimum condition is established via a systematic screening and utilized for the synthesis of four indolocarbazole aglycones with a satisfied yield. |
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