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The Study of Anti-tumor Activity of Trichosanthin by Cyclic Voltammogram
Authors:Gang XU  Cheng Cai AN  Jun FENG  Yun Xiang CI  Zhang Liang CHEN
Abstract:The anti-tumor activity of Trichosanthin (TCS) has been frequently reported in recent years. In our experiments, electrochemical methods were applied to detect the effects of TCS on human leukemia cells U937. 50m g/ml TCS treatment for 40 hours can cause irreversible negative effects on the viability of U937 cells. This effect largely depends on the concentration of TCS and the time period of treatment.
Keywords:Trichosanthin (TCS)   U937 cells   cyclic voltammogram   Ribosome Inactivating Proteins (RIPs)
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