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Reaction Between 5-Isopropylidene-2,2-dimethyl-1,3-dioxane-4,6-dione and <Emphasis Type="Italic">tert</Emphasis>-Butyl Isocyanide in the Presence of Primary or Secondary Amines
Authors:Email author" target="_blank">Issa?YavariEmail author  Azizollah?Habibi  Mohammad R?Hosseini-Tabatabaei  Hamid R?Bijanzadeh
Institution:(1) Department of Chemistry, University of Tarbiat Modarres, Tehran, Iran, IR;(2) Department of Chemistry, Islamic Azad University, Zahedan, Iran, IR
Abstract:Summary. 5-Isopropylidene-2,2-dimethyl-1,3-dioxane-4,6-dione (the condensation product of Meldrumrsquos acid and acetone) reacts smoothly with tert-butyl isocyanide in the presence of primary or secondary amines to produce N-tert-butyl-2,2-dimethylbutyramide derivatives and/or 1-tert-butyl-4,4-dimethyl-2,5-dioxopyrrolidine-3-carboxamides in good yields.
Keywords:s acid, Alkyl isocyanides, Triamides, Amidosuccinimides, Ugi reaction," target="_blank">,Meldrumrsquos acid, Alkyl isocyanides, Triamides, Amidosuccinimides, Ugi reaction,
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