有机磷化合物的研究XIX.III亚磷酸二烷基酯钠的相转移催化P-烷基化反应

Studies on organophosphorus compounds XIX. phase-transfer catalyzed p-alkylation of sodium dialkyl phosphite

Sodium dialkyl phosphite reacts with non-activated alkyl halide in the presence of crown ether to give dialkyl alkyl phosphonate in moderate yield. Little or no reaction takes place in the absence of crown ether under the same conditions. In all cases, crown ether was present in catalytic amts. indicating that it behaves as a phase transfer catalyst between solid and liquid phases. The influences of structures of crown ethers, alkyl halides, dialkyl phosphites and the nature of solvent on the P-alkylation of sodium dialkyl phosphite have been investigated.