Synthesis of 2-phenyl pyridine derivatives from aryl ketones and 1,3-diaminopropane using palladium acetate as a catalyst |
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| Authors: | Shrikant M. Ghodse Vikas N. Telvekar |
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| Affiliation: | Department of Pharmaceutical Sciences & Technology, Institute of Chemical Technology, Matunga, Mumbai 400 019, India |
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| Abstract: | A simple and efficient method for the synthesis of 2-phenyl pyridine via cyclization of aryl ketone with 1,3-diaminopropane using palladium acetate is established. This method is mild, operationally simple, involves short reaction time and involves easy workup procedure to afford the corresponding 2-phenyl pyridines in moderate to good yield. |
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| Keywords: | Aryl ketone 1,3-Diaminopropane Phenyl pyridine Palladium acetate |
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