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Hydroarylation of alkynes and alkenes through alumina-sulfuric acid catalyzed regioselective CC bond formation
Authors:Amit Pramanik  Avishek Ghatak  Sagar Khan  Sanjay Bhar
Affiliation:1. Department of Chemistry, Taki Government College, Taki, North 24 Pgs, Pin-743 429, India;2. Department of Chemistry, Dr. A.P.J Abdul Kalam Govt. College, Newtown, Kolkata 700156, India;3. Department of Chemistry, Organic Chemistry Section, Jadavpur University, Kolkata 700 032, India
Abstract:A highly atom-efficient synthetic protocol for hydroarylation of terminal-aryl alkynes and styrene through the regioselective C/>C bond formation via the electrophilic addition of naphthols and substituted phenols has been developed using alumina-sulfuric acid as a heterogeneous supported solid acid catalyst. This methodology shows excellent regioselectivity and affords the desired product in good to excellent yield. The heterogeneous catalyst can also be recycled efficiently without much loss of activity.</td>
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Keywords:Catalysis  Regioselection  Supported reagents/reactions  Sulfuric acid and derivatives
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