Central nervous system depressants. 15. 1,4-benzodiazepines |
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Authors: | Robert Bruce Moffett Bharat V Kamdar |
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Abstract: | A number of 5-phenyl-1,4-benzodiazepines and a few 2-phenyl-1,4-benzodiazepines were prepared and screened for central nervous system activity in mice. Some were highly active. An unusual substitution of 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one by trichloro-acetylisocyante is reported. |
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