Abstract: | 5,6-Dimethylbenzc]acridines, functionalized in the 7-position by the carboxy, carbomethoxy, carboxamido, N-ethylcarboxamido, acetyl, cyano, chloro, methoxy or amino group are reported for the first time. Also various related 5,5-dimethyl-5,6-dihydrobenzc]acridines including the 7-carbomethoxy, 6-hydroxy-7-carboxy, 6-bromo-7-carbomethoxy, 6-methoxy-7-carboxy, 6-methoxy-7-carbomethoxy, and 6-hydroxy-7-N-ethylcarboxamido derivatives which serve as precursors to the completely aromatized 5,6-dimethylbenzc]acridines are also reported for the first time. |