Synthesis and properties of 4-(3-amino-2-benzofuranyl)-coumarins |
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| Authors: | M S Frasinyuk S V Gorelov S P Bondarenko V P Khilya |
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| Institution: | (1) University of Auvergne, Pharmacy Department, 28 Place Henri Dunant, Clermont-Ferrand, France;(2) Samara State University, 1 Acad. Pavlov St., Samara, 443011, Russia |
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| Abstract: | The alkylation of o-cyanophenol by 4-chloromethylcoumarins and subsequent intramolecular condensation by the cyano and methylene
groups gives substituted 4-(3-amino-2-benzo-furanyl)coumarins. We studied the reactions of these compounds with acylating
agents as well as with aldehydes, which lead to the 6H-1]benzofuro3,2-b]chromeno4,3-d]pyridin-6-one system as the result
of consecutive transformations. |
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| Keywords: | |
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