|
|||||
|
|
Stereomeric studies on the oxidation and alkylation of 4-thiazolidinones |
|
| Authors: | Aina Colombo Dolors Fernández-Forner Fernando Albericio Pilar Forns |
| Institution: | a Almirall-Barcelona Science Park Unit, Barcelona Science Park, Josep Samitier 1, 08028 Barcelona, Spain b Laboratorios Almirall, S.A., Research Center, Crta. Laureà Miró 390, 08980 Sant Feliu de Llobregat, Spain c Institute for Research in Biomedicine, Barcelona Science Park, Josep Samitier 1, 08028 Barcelona, Spain |
| Abstract: | Diastereoselectivity in the oxidation of different 4-thiazolidinones was discussed. Alkylation of these compounds with benzyl bromide was also studied. The stereoselectivity obtained was interpreted by the presence of the sulfoxide. |
| Keywords: | Reaction mechanism Stereoselectivity Sulfone Sulfoxide |
| 本文献已被 ScienceDirect 等数据库收录！ | |