| Cu（OAc）2 catalyzed Sonogashira cross-coupling reaction in amines |
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| 引用本文： | Sheng Mei Guo Chen Liang Deng Jin Heng Li. Cu（OAc）2 catalyzed Sonogashira cross-coupling reaction in amines[J]. 中国化学快报, 2007, 18(1): 13-16. DOI: 10.1016/j.cclet.2006.11.019 |
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| 作者姓名： | Sheng Mei Guo Chen Liang Deng Jin Heng Li |
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| 作者单位： | Key Laboratory of Chemical Biology ＆ Traditional Chinese Medicine Research （Ministry of Education）, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China |
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| 基金项目： | 教育部科学技术研究项目;湖南省教育厅科研项目;国家自然科学基金 |
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| 摘 要： | A simple Cu(OAc)_2 catalyzed Sonogashira coupling protocol is presented.It was found that the couplings of a variety of aryl halides with terminal alkynes were conducted smoothly to afford the corresponding desired products in moderate to excellent yields,using Cu(OAc)_2 as the catalyst and Et3N as the solvent.
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| 关 键 词： | Cu（OAc）2 催化 胺类 Sonogashira交叉偶联反应 |
| 收稿时间： | 2006-05-15 |
Cu(OAc)2 catalyzed Sonogashira cross-coupling reaction in amines |
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| Sheng Mei Guo,Chen Liang Deng,Jin Heng Li. Cu(OAc)2 catalyzed Sonogashira cross-coupling reaction in amines[J]. Chinese Chemical Letters, 2007, 18(1): 13-16. DOI: 10.1016/j.cclet.2006.11.019 |
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| Authors: | Sheng Mei Guo Chen Liang Deng Jin Heng Li |
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| Affiliation: | Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China |
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| Abstract: | A simple Cu(OAc)_2 catalyzed Sonogashira coupling protocol is presented.It was found that the couplings of a variety of aryl halides with terminal alkynes were conducted smoothly to afford the corresponding desired products in moderate to excellent yields,using Cu(OAc)_2 as the catalyst and Et3N as the solvent. |
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| Keywords: | Cu(OAc)2 Sonogashira cross-coupling reaction Aryl halide Alkyne |
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