血清胆碱酯酶水平在脓毒症患者诊断中的应用价值分析

目的分析脓毒症患者胆碱酯酶含量及其与降钙素原的相关性,为早期诊断脓毒症提供一个新的初筛检测敏感性指标。方法选择60例脓毒症患者为观察组,另选择同期非脓毒症患者60例作为对照组,测定两组患者血清胆碱酯酶活性,且测定观察组PCT含量,分析PCT与胆碱酯酶的相关性。结果观察组胆碱酯酶含量明显高于对照组,差异有统计学意义(P0.05);胆碱酯酶与降钙素原呈现一定线性相关,相关性曲线为:y=2 325.23 x+239 882.3(r=0.843)。结论血清胆碱酯酶结果与降钙素原呈现一定线性关系,可考虑用于早期评估脓毒症及预后情况。

Anlysis of Value of Serum Cholinesterase Levels in Diagnosis of Patients With Sepsis

Objective To analyze the content of cholinesterase in patients with sepsis and relevance with procalcitonin , to provide a new screening test ensitive indicators for early diagnosis of sepsis .Methods 60 cases of sepsis were selected as the observation group , another 60 cases of non-septic patients were selected as the control group , serum cholinesterase activity of the two groups and the content of PCT in observation group were detected , analysis of the correlation between PCT and cholinesterase .Results The cholinesterase in observation grou was significantly higher than control group , the difference was statistically significant ( P <0.05 ); cholinesterase and procalcitonin showed some linear correlation curve:y=2 325.23 x+239 882.3 ( r=0.843 ) .Conclusion The serum cholinesterase showed some linear correlation with procalcitonin , can be considered for early evaluation and prognosis of sepsis .