超声指标对类风湿关节炎的疗效评估价值

目的探究超声指标在类风湿性关节炎(RA)治疗效果评估方面的临床价值。方法选取2014年5月到2016年5月期间于彭泽县人民医院治疗RA的50例患者(膝关节80个),观察其膝关节的肿胀体征和压痛症状,对其C反应蛋白(CRP)与血沉(ESR)进行检测,并使用超声对膝关节进行扫描,评估其骨侵蚀、灰阶滑膜炎以及能量多普勒(PD)信号。结果 1超声检查阳性率:PD为18.75%(15/80),滑膜炎为83.75%(67/80),骨侵蚀为31.25%(25/80)。2临床检查阳性率:压痛为42.5%(34/80),肿胀为33.75%(27/80)。超声的滑膜炎阳性和膝关节的压痛、肿胀阳性分别比较,前者高于后两者,且与后两者均存在统计学差异(P0.05)。行相关性分析,滑膜炎阳性、PD阳性与CRP和ESR均有相关性(P0.05),而骨侵蚀仅与CRP有相关性(P0.05),与ESR则无相关性(P0.05)。结论超声与炎性指标之间有相关性,其敏感性要优于临床检查,更适用于RA的疗效评估。

Value of Ultrasound in Evaluating the Therapeutic Efficacy of Rheumatoid Arthritis

Objective To explore the clinical value of ultrasound in the treatment of rheumatoid arthritis. Methods 50 cases selected from May 2014 to May 2016 period in our hospital patients ( 80 knees) , signs and symptoms were swelling tenderness in the knee, to detect the C of C-reactive protein and erythrocyte sedimentation rate, and scan of the knee using ultrasound, to evaluate the bone erosion, synovitis and power Doppler signals. Results The positive rate of ultrasonography:18. 75% (15/80), 83. 75% ( 67/80 ) , synovitis, bone erosion was 31. 25% ( 25/80 ) . The positive rate of clinical examination was 42. 5% (34/80) and 33. 75% (27/80). Ultrasound synovitis of knee joint tenderness, positive and positive swelling were compared, the former is higher than the latter two, and both were significantly different ( P<0. 05 ) . The correlation analysis, positive, positive and synovitis were correlated ( P<0. 05 ) , but only with bone erosion correlation ( P<0. 05 ) , and no correlation ( P>0. 05 ) . Conclusion There is a correlation between ultrasound and inflammatory parameters, and its sensitivity is better than clinical examination.