Palladium-catalyzed benzylation of active methine compounds without additional base: remarkable effect of 1,5-cyclooctadiene |
| |
Authors: | Kuwano Ryoichi Kondo Yutaka |
| |
Institution: | Department of Chemistry, Graduate School of Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan. rkuwascc@mbox.nc.kyushu-u.ac.jp |
| |
Abstract: | reaction: see text] The palladium complex prepared from DPPF and Cp(eta3-C3H5)Pd is an effective catalyst for the alkylation of active methine compounds with benzylic carbonates under neutral conditions. The addition of 1,5-cyclooctadiene brought about remarkable improvement in the lifetime of the palladium catalyst, which led to high yields of the desired benzylation products. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|