The isolation of a metastable conglomerate using a combined computational and controlled crystallization approach |
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| Authors: | Davey Roger J Sadiq Ghazala Back Kevin Wilkinson Laura Seaton Colin C |
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| Affiliation: | School of Chemical Engineering and Analytical Science, University of Manchester, Oxford Road, Manchester M13 9PL, UK. roger.davey@manchester.ac.uk |
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| Abstract: | While the use of additives to control the crystallization of polymorphs is well known, similar methodology to promote the crystallization of a metastable conglomerate over a stable racemic compound in enantiomeric systems has not been reported. Here we demonstrate this phenomenon in the case of 2-chloromandelic acid. |
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