Synthesis and structures of benzo[cd]furo[2,3-f]indol-4(5H)-one derivatives |
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| Authors: | I. G. Davydenko Yu. L. Slominskii O. I. Kalchenko A. V. Gutov A. N. Chernega A. I. Tolmachev |
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| Affiliation: | (1) College of Horticulture and Landscape Architecture, Southwest University, 400715 Chongqing, China;(2) Department of Oncology, The Ninth People’s Hospital of Chongqing, 400700 Chongqing, China;(3) College of Pharmaceutical Sciences, Southwest University, 400715 Chongqing, China;(4) Department of Chemistry, Changwon National University, 641-773 Changwon, South Korea; |
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| Abstract: | A procedure was developed for the synthesis of derivatives of the new heterocyclic system, benzo[cd]furo[2,3-f]indole, based on the cyclodehydration of 6-acylmethyloxy-1-alkyl-benzo[cd]indol-2(1H)-ones. Either 7- or 8-aryl derivatives of benzo[cd]furo[2,3-f]indol-4(5H)-ones can be prepared depending on the reaction conditions. The molecular and crystal structures of 7- and 8-phenylbenzo[cd]furo[2,3-f]indol-4(5H)-ones were established by X-ray diffraction. |
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