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Synthesis and structures of benzo[<Emphasis Type="Italic">cd</Emphasis>]furo[2,3-<Emphasis Type="Italic">f</Emphasis>]indol-4(5<Emphasis Type="Italic">H</Emphasis>)-one derivatives
Authors:I G Davydenko  Yu L Slominskii  O I Kalchenko  A V Gutov  A N Chernega  A I Tolmachev
Institution:(1) College of Horticulture and Landscape Architecture, Southwest University, 400715 Chongqing, China;(2) Department of Oncology, The Ninth People’s Hospital of Chongqing, 400700 Chongqing, China;(3) College of Pharmaceutical Sciences, Southwest University, 400715 Chongqing, China;(4) Department of Chemistry, Changwon National University, 641-773 Changwon, South Korea;
Abstract:A procedure was developed for the synthesis of derivatives of the new heterocyclic system, benzocd]furo2,3-f]indole, based on the cyclodehydration of 6-acylmethyloxy-1-alkyl-benzocd]indol-2(1H)-ones. Either 7- or 8-aryl derivatives of benzocd]furo2,3-f]indol-4(5H)-ones can be prepared depending on the reaction conditions. The molecular and crystal structures of 7- and 8-phenylbenzocd]furo2,3-f]indol-4(5H)-ones were established by X-ray diffraction.
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