Interaction of 5-Aryl-2,3-dihydrofuran-2,3-diones with Functionally Substituted Hydrazides and Diaminoglyoxal Diphenylhydrazone |
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| Authors: | D D Nekrasov S V Kol'tsova M A Radishevskaya |
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| Institution: | (1) Institute of Technical Chemistry, Urals Branch, Russian Academy of Sciences, Perm, 614990, Russia;(2) Perm D. N. Pryanishnikov Agricultural Academy, Perm, 614990, Russia |
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| Abstract: | The reaction of 5-aryl-2,3-dihydrofuran-2,3-diones with cyanoacetylhydrazide, o-(hydrazinocarbonyl)phenylthiourea, and the diphenylhydrazone of diaminoglyoxal leads to the synthesis of the corresponding N-cyanoacetylhydrazides of aroylpyruvic acids, 2-(N-aroylpyruvoylhydrazinocarbonyl)-phenylthioureas, and 5,6-bis(phenylhydrazono)-3-aroylmethylenepiperazin-2-ones. The results of the primary investigation of the biological activity of N-cyanoacetylhydrazides of aroylpyruvic acids are given. |
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| Keywords: | 5-aryl-2 3-dihydrofuran-2 3-diones aroylpyruvoylhydrazides 5 6-bis(phenylhydrazono)-3-aroylmethylenepiperazin-2-ones biological activity decyclization recyclization |
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