Jaspolides A-F, six new isomalabricane-type terpenoids from the sponge Jaspis sp |
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Authors: | Tang Shengan Pei Yuehu Fu Hongzheng Deng Zhiwei Li Jun Proksch Peter Lin Wenhan |
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Affiliation: | State Key Laboratory of Natural and Biomimetic Drugs, Peking Univesity, Beijing, People's Republic of China. |
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Abstract: | A chemical investigation of Jaspis sp., the marine sponge collected from the South China Sea led to the isolation of six new isomalabaricane-type compounds, jaspolides A-F (1-6). The structures of those compounds were elucidated by extensive spectroscopic methods. The structure-types of 1 to 6 could be classified into triterpenes (1, 2), sesterterpene (6), diterpenes (3, 4), and nortriterpene (5). The biogenetic transformation of the isolated compounds was also speculated. |
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