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Rapid and efficient synthesis of 2-substituted-tetrahydropyrido[3,4-b]quinoxalines using TDAE strategy
Authors:Omar Khoumeri  Marc Montana  Thierry Terme  Patrice Vanelle
Affiliation:Aix-Marseille Univ, CNRS, Institut de Chimie Radicalaire ICR, UMR 7273, Laboratoire de Pharmaco-Chimie Radicalaire, Faculté de Pharmacie, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
Abstract:We report herein an original and rapid synthesis of substituted 2-tosyl-1,2,3,4-tetrahydropyrido[3,4-b]quinoxaline derivatives by TDAE strategy from 2,3-bis(bromomethyl)quinoxaline and N-(toluenesulfonyl)benzylimines.
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