A novel route to synthesis of flavones from salicylaldehyde and acetophenone derivatives |
| |
| Authors: | Koneni V Sashidhara Manoj Kumar Abdhesh Kumar |
| |
| Institution: | Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, (CSIR–CDRI), Lucknow 226 001, India |
| |
| Abstract: | Convenient, facile, and alternate synthesis of medicinally important flavones is reported. The 2-hydroxychalcones derived from condensation between acetophenones and salicylaldehyde, underwent oxidative cyclization on heating in the presence of catalytic iodine, generating diversified flavones under solvent-free conditions. Eleven compounds have been synthesized in good to excellent yields and their mechanism of formation is described. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
