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A Novel Quinazolinone Derivative as Fluorescence Quenching Off-On Sensor for High Selectivity of Fe3+
Authors:Ailin Yuan  Chunling Zheng  Zhengyu Zhang  Lu Yang  Chao Liu  Haibo Wang
Institution:1. Institute of Food and Light-chemical Engineering, Nanjing, Jiangsu, China
Abstract:A novel quinazolinone compound containing quinazoline-fused moiety has been synthesized as fluorescence Off-On sensor QQ. The probe exhibited highly selective and sensitive recognition toward trivalent ferric ion (Fe3+) over other metal ions in HEPES buffer solution (10 mM, pH?=?7.0, DMF-H2O, 9:1, v/v). The significant quenching in the fluorescence spectral could be served as a selective fluorescence Off-On sensor. The titration study indicated the formation of 1:1 complex between QQ and Fe3+.
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