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Evaluation of antioxidant capacity and synergistic associations of quinonemethide triterpenes and phenolic substances from Maytenus ilicifolia (Celastraceae)
Authors:Dos Santos Vânia Aparecida de Freitas Formenton Macedo  Dos Santos Daniela Pereira  Castro-Gamboa Ian  Zanoni Maria Valnice Boldrin  Furlan Maysa
Affiliation:Núcleo de Bioensaios, Biossíntese e Ecofisiologia de Produtos Naturais-NuBBE-Departamento de Química Organica, Instituto de Química, Universidade Estadual Paulista, UNESP, CP 355,14801-970 Araraquara-SP, Brazil.
Abstract:This work describes the isolation of the secondary metabolites identified as the quinonemethides maytenin (1) and pristimerin (2) from Maytenus ilicifolia extracts obtained from root barks of adult plants and roots of seedlings and their quantification by high performance liquid chromatography coupled to a diode array detector. The electrochemical profiles obtained from cyclic voltammetry and a coulometric detector coupled to high-performance liquid chromatography contributed to the evaluation of their antioxidant capacity. The antioxidant properties of individual components and the crude extracts of the root barks of Maytenus ilicifolia were compared and the possible synergistic associations of quinonemethide triterpenes and phenolic substances were investigated by using rutin as a model phenolic compound.
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