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Asymmetric microbial conversion of (E)-2-benzylideneindan-1-one by the filamentous fungi Botrytis cinerea,Trichoderma viride,and Eutypa lata
Authors:Cristina Pinedo-Rivilla  Josefina Aleu  Isidro G Collado
Institution:Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Campus de Excelencia Internacional Agroalimentario, ceiA3, República Saharaui s/n, Apdo. 40, 11510 Puerto Real, Cádiz, Spain
Abstract:The transformation of (E)-2-benzylideneindan-1-one 1 by the filamentous fungi Botrytis cinerea, Trichoderma viride, and Eutypa lata as biocatalysts was studied. The results showed the catalytic potential of these fungi in affording several hydroxylation and reduction products, three of them reported here for the first time. The absolute configuration of enantiomerically pure 2-benzylindane derivatives was determined.
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