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A Clean Synthesis of 1,4‐Diarylquinoline Derivatives Catalyzed by TEBAC in Aqueous Media
Authors:Xiang‐Shan Wang  Mei‐Mei Zhang  Hong Jiang  Da‐Qing Shi  Shu‐Jiang Tu
Affiliation:1. Department of Chemistry, Xuzhou Normal University, Xuzhou Jiangsu 221116, P. R. China;2. The Key Laboratory for Biotechnology on Medical Plants of Jiangsu Province, 221116, P. R. China
Abstract:A series of 1,4‐diarylquinoline derivatives were synthesized by the reaction of arylmethylidenemalononitriles or 2‐cyano‐3‐aryl‐1‐acrylate and 3‐arylamino‐5,5‐dimethylcyclohex‐2‐enone in aqueous media at 100 °C catalyzed by TEBAC. Meanwhile, the water medium was chosen as green solvent.
Keywords:Quinoline  TEBAC  Aqueous media  Synthesis
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