Easily Accessible 2‐(2‐Bromophenyl)‐4,4,5,5‐Tetramethyl‐[1,3,2]Dioxaborolane for Suzuki‐Miyaura Reactions |
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| Authors: | Tein‐Fu Wang Ching‐Lung Lin Chih‐Neng Chen Tan‐Ching Wang |
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| Institution: | 1. Institute of Chemistry, Academia Sinica, Taipei, Taiwan, R.O.C.;2. Department of Chemistry, National Central University, Chung‐Li, Taiwan, R.O.C. |
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| Abstract: | A simple and direct method has been developed for the preparation of the title compound from 1,2‐dibromobenzene. Suzuki‐Miyaura reactions of this compound with substituted bromoaryls proceeded smoothly to give 2‐bromobiphenyl derivatives in moderate to excellent yields. Instead of converting each of the bromoaryl compounds to the corresponding arylmetals followed by reacting with 2‐iodobromobenzene, the advantage of this protocol is that the substituted bromoaryls were used directly to couple with the title compound. |
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| Keywords: | Suzuki Biphenyl Coupling Spirobifluorene |
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