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Synthesis and Reactions of Naphtho[1′,2′:4,5]Furo[3,2‐b]Pyridine and Naphtho[1′,2′:4,5]Furo[3,2‐d]Pyrimidine Derivatives
Authors:M. Z. A. Badr  A. M. Kamal El‐Dean  O. S. Moustafa  R. M. Zaki
Affiliation:Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt
Abstract:2‐Acyl‐3‐aminonaphtho[2,1‐b]furan ( 1 ) reacts with activated methylene such as malono nitrile or ethyl cyanoacetate to afford naphtho[1′,2′:4,5]furo[3,2‐b]pyridine 2a,b . Chloroacylation of the amino group in compound ( 1 ) gave compound 3 which reacts with different amines to produce compound 4 .
Keywords:Synthesis  Reactions  Naphthofuran  Naphthofuropyridines  Naphthofuropyrimidines
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