Sesquiterpene Coumarins from Ferula Foetida |
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| Authors: | Mohamed H Abd El‐Razek Yang‐Chang Wu Fang‐Rong Chang |
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| Institution: | 1. National Research Center, Chemistry of Natural Compounds Department, El‐Tahrir St., Dokki, Cairo 12622, Cairo, Egypt;2. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, R.O.C. |
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| Abstract: | A thorough investigation of the ethyl acetate soluble fraction from a methanol extract of the resin of Ferula foetida has resulted in the isolation of a new sesquiterpene coumarin namely epi‐conferdione ( 1 ), along with four known compounds, colladonin ( 2 ), karatavicinol ( 3 ), 8‐acetoxy‐5‐hydroxyumbelliprenin ( 4 ), and asacoumarin ( 5 ). These structures were elucidated on the basis of extensive spectroscopic techniques, including 1D and 2D NMR spectroscopy. The absolute configuration of the new compound was established by circular dichroism (CD). |
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| Keywords: | Ferula foetida Umbelliferae Resin Sesquiterpene coumarin CD |
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