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Microwave‐assisted efficient synthesis of benzo[4,5]imidazo[1,2‐a]‐pyrimidine derivatives in water under catalyst‐free conditions
Authors:Shujiang Tu  Qingqing Shao  Dianxiang Zhou  Longji Cao  Feng Shi  Chunmei Li
Institution:Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology on Medical Plant, Xuzhou, Jiangsu 221116, PR China
Abstract: chemical structure image Benzo4,5]imidazo1,2‐a]pyrimidine derivatives were synthesized via the three‐component reaction of aldehyde, β‐dicarbonyl compound and 2‐aminobenzimidazole in water under microwave irradiation and without catalyst conditions. The new protocol has the advantages of higher yield, lower cost, reduced environment impact, wider scope and convenient procedure.
Keywords:
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