An Efficient Synthesis of Pyrazolo[3,4‐b]Pyridine Derivatives in Aqueous Media |
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Authors: | Da‐Qing Shi Jing‐Wen Shi Hao Yao Hong Jiang Xiang‐Shan Wang |
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Affiliation: | 1. College of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University, Suzhou 215123, P. R. China;2. Department of Chemistry, Xuzhou Normal University, Xuzhou 221116, P. R. China;3. Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province Xuzhou Normal University, Xuzhou 221116, P. R. China |
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Abstract: | A series of pyrazolo[3,4‐b]pyridines was synthesized by the reaction of 5‐aminopyrazole with benzylidenemalononitrile in aqueous media. The structures were characterized by IR, 1H NMR, and elemental analysis and were further confirmed by X‐ray diffraction analysis. |
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Keywords: | Pyrazolo[3,4‐b]pyridine 5‐Aminopyrazole Benzylidenemalononitrile Aqueous media |
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