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An Efficient Synthesis of Pyrazolo[3,4‐b]Pyridine Derivatives in Aqueous Media
Authors:Da‐Qing Shi  Jing‐Wen Shi  Hao Yao  Hong Jiang  Xiang‐Shan Wang
Affiliation:1. College of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University, Suzhou 215123, P. R. China;2. Department of Chemistry, Xuzhou Normal University, Xuzhou 221116, P. R. China;3. Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province Xuzhou Normal University, Xuzhou 221116, P. R. China
Abstract:A series of pyrazolo[3,4‐b]pyridines was synthesized by the reaction of 5‐aminopyrazole with benzylidenemalononitrile in aqueous media. The structures were characterized by IR, 1H NMR, and elemental analysis and were further confirmed by X‐ray diffraction analysis.
Keywords:Pyrazolo[3,4‐b]pyridine  5‐Aminopyrazole  Benzylidenemalononitrile  Aqueous media
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