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Synthesis of substituted 3‐pyrrolidinecarbonitriles
Authors:Hiroshi Maruoka  Fumi Okabe  Kenji Yamagata
Affiliation:Faculty of Pharmaceutical Sciences, Fukuoka University, 8‐19‐1 Nanakuma, Jounan‐ku, Fukuoka 814‐0180, Japan
Abstract: chemical structure image Cyclopropanes substituted at the same ring carbon by two electron‐withdrawing groups such as alkoxycarbonyl or cyano group react with the primary arylamines via a ring‐opening reaction and ensuing intramolecular cyclization to form substituted pyrrolidines.
Keywords:
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