Faculty of Pharmaceutical Sciences, Fukuoka University, 8‐19‐1 Nanakuma, Jounan‐ku, Fukuoka 814‐0180, Japan
Abstract:
Cyclopropanes substituted at the same ring carbon by two electron‐withdrawing groups such as alkoxycarbonyl or cyano group react with the primary arylamines via a ring‐opening reaction and ensuing intramolecular cyclization to form substituted pyrrolidines.