1. Department of Chemistry, University of Arak, Dr. Beheshti, Ave, Arak‐Iran;2. Department of Chemistry, University of Imam Hossein, Tehran‐Iran
Abstract:
A series of oxo‐ and thioxopyrimidines 4 ( a‐m ) were synthesized by one‐pot three components cyclocondensation reaction of β‐ketoester, aldehyde and urea/thiourea using benzyltriethylammonium chloride as a catalyst under solvent‐free conditions. The yields of products following recrystallization from ethanol were of the order of 65‐87%. IR and 1HNMR spectroscopy and elemental analysis were used for identification of these compounds.